Quarterly report pursuant to Section 13 or 15(d)

Assumptions Used in Estimating Fair Value of Stock Options Granted (Detail)

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Assumptions Used in Estimating Fair Value of Stock Options Granted (Detail) - 2002 Stock Incentive Plan
3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Expected term 5 years 4 months 24 days 5 years 7 months 6 days 5 years 7 months 6 days 5 years 8 months 12 days
Volatility 77.60% 83.80% 78.50% 84.80%
Risk-free interest rate 1.98% 1.32% 1.98% 1.34%